Swamy Yeleswaram Selected Research

pemigatinib

1/2022	Evaluation of the clinical cardiac safety of pemigatinib, a fibroblast growth factor receptor inhibitor, in participants with advanced malignancies.
1/2022	Evaluation of the pharmacokinetics of pemigatinib in patients with impaired hepatic or renal function.
1/2022	Population Pharmacokinetics Analysis of Pemigatinib in Patients With Advanced Malignancies.
1/2020	INCB054828 (pemigatinib), a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3, displays activity against genetically defined tumor models.

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Swamy Yeleswaram Research Topics

Disease

16	Neoplasms (Cancer) 01/2022 - 05/2005
5	Primary Myelofibrosis (Myelosclerosis) 10/2018 - 11/2010
4	Atopic Dermatitis (Atopic Eczema) 05/2022 - 09/2011
4	Psoriasis (Pustulosis Palmaris et Plantaris) 07/2021 - 09/2011
3	Cholangiocarcinoma 01/2022 - 01/2022
3	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2021 - 01/2020
2	Chronic Kidney Failure (Chronic Renal Failure) 01/2022 - 01/2020
2	Skin Diseases (Skin Disease) 07/2021 - 09/2011
2	Autoimmune Diseases (Autoimmune Disease) 11/2020 - 05/2010
2	Cytokine Release Syndrome 07/2020 - 01/2020
2	COVID-19 07/2020 - 01/2020
2	Hematologic Neoplasms (Hematological Malignancy) 01/2020 - 01/2018
2	Multiple Myeloma 01/2019 - 01/2018
2	Rheumatoid Arthritis 12/2014 - 05/2010
2	Body Weight (Weight, Body) 07/2013 - 05/2005
2	Arthritis (Polyarthritis) 05/2010 - 10/2005
1	Type 2 Diabetes Mellitus (MODY) 01/2022
1	Vitiligo 07/2021
1	Alopecia Areata 07/2021
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 07/2020
1	Fatigue 01/2020
1	Nausea 01/2020
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2020
1	Thrombocytopenia (Thrombopenia) 01/2020
1	Lymphoma (Lymphomas) 01/2020
1	Bronchiolitis Obliterans Syndrome 12/2019
1	Serotonin Syndrome (Syndrome, Serotonin) 01/2019
1	Cytopenia 10/2018
1	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2018
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2018
1	Carcinogenesis 01/2018
1	Breast Neoplasms (Breast Cancer) 01/2017
1	Nasopharyngitis 08/2016
1	Wernicke Encephalopathy (Wernicke's Encephalopathy) 10/2014
1	Thiamine Deficiency 10/2014
1	Essential Thrombocythemia 07/2013
1	Polycythemia Vera 07/2013
1	Pain (Aches) 01/2012

Drug/Important Bio-Agent (IBA)

12	ruxolitinibIBA 05/2022 - 11/2010
10	Janus KinasesIBA 07/2021 - 06/2012
7	CytokinesIBA 07/2021 - 05/2010
4	pemigatinibIBA 01/2022 - 01/2020
4	Phosphotransferases (Kinase)IBA 01/2022 - 10/2012
4	itacitinibIBA 01/2021 - 12/2019
3	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 01/2022 - 01/2020
3	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 11/2020 - 01/2018
3	Janus Kinase 1IBA 01/2020 - 07/2013
3	Proteins (Proteins, Gene)FDA Link 01/2019 - 01/2017
3	EnzymesIBA 01/2017 - 12/2011
3	Interleukin-23 (Interleukin 23)IBA 10/2012 - 05/2010
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021 - 12/2019
2	parsaclisibIBA 11/2020 - 01/2020
2	INCB054329IBA 01/2020 - 01/2019
2	InterleukinsIBA 01/2019 - 10/2012
2	Peptides (Polypeptides)IBA 01/2017 - 02/2010
2	baricitinibIBA 12/2014 - 05/2010
2	Investigational DrugsIBA 10/2014 - 11/2010
2	Matrix Metalloproteinases (MMPs)IBA 02/2010 - 05/2005
2	Doxorubicin (Adriamycin)FDA LinkGeneric 02/2010 - 05/2005
2	ProdrugsIBA 02/2010 - 05/2005
1	INCB 13739IBA 01/2022
1	AntibodiesIBA 01/2022
1	Programmed Cell Death 1 ReceptorIBA 01/2022
1	Type 1 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 1)IBA 01/2022
1	Glucose (Dextrose)FDA LinkGeneric 01/2022
1	tyrosine receptor (receptor, tyrosine)IBA 01/2022
1	LigandsIBA 01/2022
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 11/2020
1	Antiviral Agents (Antivirals)IBA 01/2020
1	INCB057643IBA 01/2020
1	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2020
1	VaccinesIBA 01/2020
1	Pharmaceutical PreparationsIBA 01/2020
1	Cisplatin (Platino)FDA LinkGeneric 01/2020
1	Tryptophan (L-Tryptophan)FDA Link 01/2019
1	Serotonin (5 Hydroxytryptamine)IBA 01/2019
1	Janus Kinase InhibitorsIBA 10/2018
1	Antineoplastic Agents (Antineoplastics)IBA 01/2018
1	Bendamustine Hydrochloride FDA Link 01/2018
1	Cytarabine (Cytosar-U)FDA LinkGeneric 01/2018
1	IsoenzymesIBA 01/2018
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2018
1	Organic Anion TransportersIBA 01/2017
1	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 01/2017
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2017
1	epacadostatIBA 01/2017
1	erythromycin propionate-N-acetylcysteinateIBA 01/2017
1	INCB039110IBA 08/2016
1	Janus Kinase 2IBA 10/2014
1	fedratinibIBA 10/2014
1	Thiamine (Aneurin)FDA Link 10/2014
1	XenobioticsIBA 10/2014
1	InterferonsIBA 10/2012
1	Cytochrome P-450 CYP3AIBA 06/2012
1	Formaldehyde (Formol)FDA Link 01/2012
1	CarrageenanIBA 01/2012

Therapy/Procedure

4	Therapeutics 07/2021 - 01/2018
1	Artificial Respiration (Mechanical Ventilation) 07/2020
1	Drug Tapering 01/2020
1	Renal Dialysis (Hemodialysis) 01/2020